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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9450e903358e4a4729f7fcb449cf9a2b27a41345ea384fb4e1abfc358e7af6' 
  AND token = 'gso+fiCQ4DekWyZfvp7e+I4q0Wl46VYBsD7IZZU4qNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}