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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd35b4a7d8360077e14a18a4e1dedfa387809aa2174ebc8c76fcadcc7ff51fe' 
  AND token = 'nwO/pQY6Gd/uy9lSxxEPIDKPqwzfjW/6IB40uO4LNr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}