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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd427ec58467f9b22331e9eafe2701215c5bf680d2a6d076bbe0f31b2cbc3ca6f' 
  AND token = 'mdrxdOgM+iEwVoG/zXcKs/4uBT7gPrNbf65LR9VOv3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}