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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c86ee2e777b4bd00dbcaa11ea265031abbb731f7895e4c63d429f98d7bfda59' 
  AND token = '8o/1q0nXC88x1haTEMvt/13tujkA3zNApRgxtux4oA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}