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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af80167d2e9dd83ef8eefd9628a865e56daa3f396b8ff4d5e57af42cb72dff2' 
  AND token = 'O4XfUA/HoLBRtjd28m6VB8uGrro01VV8LamWIvONgFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}