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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a483bad19b271d2a968be053ca834a0215f6c585614d2099c04c57feab5065ca' 
  AND token = '+Yq5LQQhB7kPCo4XXHFuG1RSh6pH50CXaWvAIzIs5So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}