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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c785f674286ad226fe53e643e37e2a9411f48eeed2184c3b318043fcdd1548' 
  AND token = 'tIRhs2OLd89L93KqzsI0wV4CbJxkc1Pg7yhFTEVo3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}