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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c226eeba57d38455a656db8fc471fab6b588d22f97f662dc05e0a5699d38e0b4' 
  AND token = 'k60Pvdmp1aEkUkxA3U/cRruXDNPATyYdmYxLMeAGyvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}