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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8f46d342b28db4afce3245d2ca40b90c9bba1090dd15629bcc6c75d730ddf8' 
  AND token = 'qEAGLgzvWDY2CXhqucbXQhf41eh4oczgbM9qnuGGGqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}