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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65a469e3507214afb62673baa7226b5b7e107ca604319862f5cf6791fbce339' 
  AND token = 'tNzQ5H9WnZ0IiZOUw+8V+ZthM4vY57QX7dTrV6zGdnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}