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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78ac12bb82434b7c228c95b67d0c901d162d64693ae0f1b93d5cf52e1ae0981' 
  AND token = 'uZnAT4+yc7QofoiM0c7mJsVB7jDWju0RQ0klri1ijbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}