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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd572e787689d4e18b4017d7b4c688448412202ccd151f272205c8799f37e29' 
  AND token = 'KF0GgSXZ4VK1Y1eoD0NdOLrlKHZCGMibnsKX/7odGFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}