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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d6e21f88ace007d54356f3b180204b94cc9a7642cb39c85696244d810c9ef4' 
  AND token = 'jR/zkcPSxYsKNTmYFysoVa/g7CAFp11zty17A5zamAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}