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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ebfe2f305e1000e00aeb5c9a8ef5c282d7a4865da3f120d2eb545e5bb06819' 
  AND token = 'CumXW6go6LPNWN+xGryK9m+vIoTJe0dWtO5F7pxdV9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}