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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888a8399217f1a0a9a19c7530eba33491690f68698b599c46a91c2655e51a024' 
  AND token = 'yZ1CLeSUVdHynilA7LPruAmC3REu0hI4BU1140v0IEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}