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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60497dc14388bc1044c752f856c2a131e86b0ca335ee2335706dc61ca89f8c7b' 
  AND token = 'YUx9UoLdv7bsW0YHXsrK7scyegnKmoXTLYP6SbH/ctI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}