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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24d948a714093828ef7f9f5aa82aed83d7746e0b0d1a2d63afc022b4d5be5483' 
  AND token = 'xCSrbrv4sdKXCL11FxKCnygstC1udgiwTH3omXWe94I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}