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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e10249f0eac8267db9d3f0f76bea4dbd402200f063e47eca5fa897d1459324' 
  AND token = 'mfHiKpN9ehMT8oJmP5+Tb1cXGG3Lf20ZAmNKF1b/uzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}