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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de73ca1a632914a22afb23e158b3234aa6be0026f6af4ec3717422ccb8a9caf' 
  AND token = 'uGMP+feU7Qe9qZwxb0iLZq4GTMAQAAsUjKrQzFN48ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}