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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125447b8d3aa5ef79cc04ad67e4a6172123e2e07ca16f77de4bd45e141fe6c58' 
  AND token = 'P61geNd39xNvjqlEAUvLnHzkutUtZNaj4F/dO8vIZic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}