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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbe4b230c2413af914a0987f81de1134c4d6cc9265f12ae426604fa46badf16' 
  AND token = 'e3lU7H38UJdNzF+k9xle1kuZ2SN3IO2FQnGAS8mDPg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}