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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412fe16a27d9c1912102e7d9adf31d87de1ce36212927a9a2d7f31d77243592a' 
  AND token = 'L25hSe+BN2ygKRIXVWqX5jV0YO8cxaKvMNvXX58mLlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}