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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdf65e6b18d81f6e7641be78a92d83331f7ceec32f776068e1284f0a288f3ee1' 
  AND token = 'WSrpRh0H8BhUhntW2xCCRQT0QgwS9ahkTVJTbjQmPp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}