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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a353d16c8ff85a9e2e954eb7891e510616903f1d5261a20c942d2a72a831d7d' 
  AND token = 'XCijIBP+9PlaAn+Vgyg0Me5DkO/EdpBSQQmtswFsl38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}