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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edf143bb5d27a9a97befe32cd230a2fc549f9bb9eba3fb4cfd8f14161418bdf6' 
  AND token = 'TrcBmAOnzoXwvNh5v98Yw4HE8OxAbfyjrBcYyaqPdPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}