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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cc10a7980c5861f27624e35cabc2ac2cc00da41ba483eb81bc4303f61449a4f' 
  AND token = 'Xjn4M2JpSczymB48SR8UuBm8oBbVh5sFPc7D/B2MI/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}