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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6cac0c41d9cffb3678f9b6f6a9ed2fa2af3392f9a639e56380f64872dfec16' 
  AND token = 'uEpzS5TjzynEmK13L4eMmCUpvIeBlzDJFJzecrtpB5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}