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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5550fef8507db3808597d66d7be723baa3e432fd03be1646e0aec9b9dc79781' 
  AND token = 'F0UYZ7G/cBS4Y4zwj4ATBq02Gxjp85TeaLep+7v7Bkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}