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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a1e5b7507f25cff3385dae148b5a7c820ceeccf428ba0a237932f45371afa2' 
  AND token = 'chKX3QRtplL23wv98wQnPseIfzq4CaXxu3s06jO2lck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}