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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce14418211d057a533d37ef14721f57669f6a6dcbf587d957fe77e8042d58286' 
  AND token = 'zLwyEf8qay2/8MRVeYBD5o/B/+fyxNqTnBSWUkN20zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}