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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a21a05a2cb1c98de4e3decdd84f8f9bcd29ec99e5a521f879de53e3fcac4ba2' 
  AND token = 'pO9f5C9Z4HklaKguOPUh/oPaJ1JN6EYTAHwEQmS4RXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}