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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce364b7a176f00e733d4ac658c8fc4abcc848bfbe798d60381620406299a7b7' 
  AND token = 'GUQX06uKvLIDCOSr2kasC1xEyPjBiVJ9vDW/pd13tGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}