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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5d91c62a0b2154436ca9a7152b2eb15518f72a77538cb892f219863e15a8e9' 
  AND token = 'CXfN1Qgdgbn6M4c6xV4kPgSlJgLTxAE0EyojdMP31SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}