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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03fd82a97eb350a7cf497dcfcacc5c3fd7f210df193a3af71d03e1c5df1161d8' 
  AND token = 'Pk9qHAlctF/z6QCH1+gqX56/QDmXfwNcCCm+35Lfmxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}