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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01d6e19f86bee5f6eb765464686e2c85723fad9feb60231cc34184fc0c43821' 
  AND token = '1P89Cy4v4zW0OPts/v5CwAxJil2YiPgVNuB30gZT73A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}