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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2447cb342c8dc21c07eda3e5e572c1bea84afb43883278545a5a0fc8738826' 
  AND token = '0DsgCsw96RdimrxsnM/3b2IzXg2zhfngi9siUuRZ9OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}