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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6cac342f74ffdda67f2ff100bdf6abf2c57fafdf0090a6122b0d235e0a90f5' 
  AND token = 'xDbIidwVLtARTBNmluwD6L/zO6bdT1zLmkG1P2+yr0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}