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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d40a479507db31c076e03a7d60b2c18f29cdc43751ae33694d287af89edc9f' 
  AND token = 'DS1pR2uCZ93r1KK3PIOU6pse86PXlYjESnYfCXQbWtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}