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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f18771202f001717321b8f0a8f7f2bbcfbbc0d0d73a932f31d2a62522e5c95' 
  AND token = 'AcSb4twiv4v2eHO5H6cwKyxt/55rpzngJcrGEiCvlgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}