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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95ba0157cf8cd97b6ca7eac244f7538050cc6cac4403948b67b60dcb4ca8864' 
  AND token = 'NUm2rQ48yB6NaN36D2PKbG7xkXOzgQYc2TlBiAFXeVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}