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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542300ddbd382e14eb1003906a37e8b04720b13cebdc0f40e5943b0a902c8938' 
  AND token = 'btCttXLINq1e2AU5iJmaYL7hOPIDQEtdIb1fL8uNydM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}