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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae7143d9db4b08113d13f2d0f5e63a8f3a35082fb6fb3b148005dada13b6482' 
  AND token = 'DMGe6XqmyB9bVnMOEfKjaKfY8FKenw8ugsi2vBTLaWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}