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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9f915d22a93cc2e273d955aaaa408495375834b5a121283ae693271f0527fd' 
  AND token = 'wcnk8v/RT0O8PXt++YSNHuv+54KobEPGKcGwHPKlCnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}