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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f483ac8a9ee149541f9e7588324536fa00b7e0a4e14900c471606fa984724f6f' 
  AND token = 'PGFe+104NZMmJXOlTtghU0XOSTWcPeJAwFVkCMojyf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}