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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba21ed47d27f020f1a3d246f7b6d777b4103f1b281ee7f6b9e993a0e29b615a' 
  AND token = 'bZl5xvAHaDuuE4syl3gEnxuxvdpmU7haxAb5rW0vpCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}