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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed556887634ee9822e44ab3c6d42c79592626d3df8fef93b672e5eacb3ef867' 
  AND token = 'UcRM/JzU/S2iFa/JOIGHPskT4LeggvbjTjASUyyGMgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}