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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581d19dc995378c47cc57c44080483d8891dbe49b17d1651b32a8013a139c4b5' 
  AND token = 'E+q1WdP1eIwfigguS6TPOOv2z1DggJOeNS34w0+m7B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}