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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd0e7faf7f5be40ef6f3e7fa945b53dc22a9364eb907ccf957213bf1c16240b' 
  AND token = '+2WUy7UPF6rb4ungFE6H1HhF/25czTSzFxygn+cQIw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}