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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343c3fbadd34fa5928b6cde0e8bc36160452c154dff8e96c063b13b58eba375d' 
  AND token = 'GE5KbCEfofzOE+DNC8dZr23frU7kw0qZJkHpkbsgtwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}