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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ab2fa666c8982dee536f85759e9b86c58c2d52091310978b3008562b53f9c0' 
  AND token = 'x8u9qypusAP+iBrH3og3VgrklHhmxrZwSgR/mSivLBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}